Ipamorelin

Selective GHRP · Ghrelin receptor agonist

Ipamorelin 10mg research vial

A pentapeptide growth-hormone secretagogue noted in the literature for its selectivity — minimal cross-activity at cortisol and prolactin pathways compared to earlier GHRPs.

Sizes

  • 10mg / vial — $100 (currently out of stock)

Specifications

  • CAS number: 170851-70-4
  • Molecular formula: C38H49N9O5
  • Molecular weight: 711.85 g/mol
  • Sequence: Aib-His-D-2-Nal-D-Phe-Lys-NH2
  • Form: Lyophilised powder
  • Storage: −20°C, protected from light

What it is

Ipamorelin is a five-amino-acid growth hormone secretagogue. Its defining property in the literature is not potency — several older compounds hit harder — but selectivity. It does one thing without dragging other endocrine axes along with it.

Background

Ipamorelin is a five-residue growth-hormone secretagogue originally developed by Novo Nordisk. It was never brought to market as a medicine and is available only as a research compound.

How it works

It binds the ghrelin receptor (GHS-R1a) in the pituitary, triggering a GH pulse. Unlike earlier GHRPs it shows minimal cross-activity at cortisol and prolactin pathways — that selectivity, not potency, is its defining property.

Why researchers order it

That clean profile makes it the standard control compound in secretagogue research — if you want to isolate the effect of a GH pulse without confounding variables, this is the molecule that lets you do it. It is almost always studied alongside CJC-1295, since the two act on separate receptors and the combination is additive.

Studied in

  • GHS-R1a selectivity and receptor-binding studies
  • Low cross-reactivity secretagogue models
  • Frequently paired with CJC-1295 in protocol research

Handling and storage

Add 2ml of bacteriostatic water for 5mg/ml. Swirl until dissolved. Store unopened vials at −20°C, protected from light; lyophilised powder is stable for years that way and tolerates shipping at ambient temperature. Solutions prepared for analysis should be held at 2–8°C, protected from light. Repeated freeze–thaw cycles compromise sample integrity.

Stability notes for this sequence

  • Lyophilised powder is stable for years at −20°C in the dark and tolerates days at ambient temperature in transit.

Specification in brief

Ipamorelin is a 6-residue peptide with the molecular formula C38H49N9O5 and a molecular weight of 711.85 g/mol, CAS registry number 170851-70-4. The vial is sealed and lot-numbered, holds lyophilised powder, and is kept at −20°C protected from light until it ships.

Sizes and price

Ipamorelin is sold per vial in one size: 10mg at $100 (currently out of stock). Any quantity can be ordered from a single vial upward; ten vials make a sealed box. Shipping is a flat $10 within the United States and free on orders of $250 or more.

Evidence at a glance

The 2 papers cited below are 1 study in humans and 1 animal study.

Also in Growth Hormone

Side by side

Further reading

References

  1. Raun K et al. (1998). Ipamorelin, the first selective growth hormone secretagogue. Eur J Endocrinol. PubMed 9849822 · SummaryIn rats and pigs, ipamorelin released growth hormone without the ACTH or cortisol release seen with GHRP-6.
  2. Gobburu JV et al. (1999). Pharmacokinetic-pharmacodynamic modeling of ipamorelin, a growth hormone releasing peptide, in human volunteers. Pharm Res. PubMed 10496658 · SummaryPharmacokinetic–pharmacodynamic model in human volunteers: dose-dependent growth hormone release with a short plasma half-life.

Questions about Ipamorelin

Is Ipamorelin for human use?

No. Everything Zyrna Research supplies is for laboratory research only. It is not for human or veterinary use, and nothing on this page is a claim of safety or efficacy.

Is there a certificate of analysis for Ipamorelin?

We forward the manufacturer's certificate for the batch in stock on request. Email before ordering and we will send the current one. We do not run our own assays and we do not publish figures we have not been given.

What sizes does Ipamorelin come in?

10mg. Vials ship in the manufacturer's sealed, lot-numbered packaging; nothing is repackaged or relabelled.

How should Ipamorelin be stored?

Unopened lyophilised vials at −20°C, protected from light. Prepared solutions at 2–8°C. Repeated freeze–thaw cycles compromise sample integrity for analytical work.

How is it shipped?

From Nashville, Monday to Friday, with carrier tracking on every order. Paid orders are handed to the carrier the next business day; domestic transit is typically 2–4 business days. Lyophilised material is shelf-stable in transit and ships at room temperature.

What if a vial arrives damaged?

Photograph it before opening anything else and email orders@zyrnaresearch.com within 72 hours of delivery. We replace it. Opened or unsealed vials cannot be returned, because storage conditions cannot be verified once they leave our control.

For laboratory research use only. Not for human or veterinary use. Nothing on this page is a claim of safety or efficacy, and none of it has been evaluated by the FDA.